hyBeads® Streptavidin

** The hyBeads product range will be discontinued as of 31 December 2017, please contact Hyglos for more information **

The superparamagnetic hyBeads® Streptavidin are designed for direct and indirect magnetic separation and purification of a wide range of target molecules (e.g. nucleic acids, antibodies, proteins, lectins and carbohydrates).

hyBeads® Streptavidin are composed of hydrophilic, cross-linked, chemical polymer and respond to magnetic fields without magnetic memory for highly efficient and rapid isolation of target molecules.

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Product information

Package insert

Streptavidin Magnetic hyBeads®, 4 x 10 mg

hyBeads® Streptavidin, 4 x 10 mg

Item no. 311092
4 x 10 mg (4 x 2.5 ml [4 mg/ml])

hyBeads®: Streptavidin Magnetic Beads

hyBeads® Streptavidin, Bulk

Item no. 800032
On request


  • Excellent magnetic properties
  • High biotin binding capacity
  • Low sedimentation rate
  • Low unspecific binding
  • Best price

Application Examples:

    • Purification of proteins and nucleic acids
    • Immunoassays / Immunodiagnostics
    • Immunoprecipitation
    • Cell isolation
    • Phage display / Biopanning

    The ligand Streptavidin, with its four identical subunits each containing high affinity binding site for biotin, enables the magnetic separation and purification of almost any biotin-linked target molecule.


    Bead size 1.52 μm (range 0.8 - 3.0 μm)
    Iron content (Magnetite) 50 - 60 % (w/w)
    Biotin binding capacity > 1,300 pmol / mg beads
    Protein binding capacity 30 - 40 μg / mg (biotinylated BSA)
    pH tolerance 4 - 10 (if tolerated by target molecule)
    Salt tolerance 0.01 - 3.0 M NaCl (if tolerated by target molecule)

    Depending on your desired application and target molecule, the direct (A) or indirect (B) capture method is applied:

    Direct Magnetic Capture Protocol

    Direct Magnetic Capturing Protocol with hyBeads Streptavidin magnetic beads
    A: Direct Magnetic Capture with hyBeads® Streptavidin

    Indirect Magnetic Capture Protocol

    Indirect Magnetic Capturing Protocol with hyBeads Streptavidin
    B: Indirect Magnetic Capture with hyBeads® Streptavidin