Hyglos GmbH is a biotech company located in Biotechnology Center Bernried, Munich area, Germany. Being an IAFP Innovation Awardee we apply our proprietary technology for developing highly specific bacteriophage-derived proteins for improved detection and removal of harmful bacteria and bacterial toxins such as endotoxins. As a company we have a strong focus on innovation in the field of Endotoxin Detection. Our highly innovative and sustainable LAL-alternative assays are based on Phage Recombinant Proteins and Recombinant Horseshoe Crab Factor C (rFC), completely without using the blood from horseshoe crabs.

Our endotoxin tests EndoLISA® and EndoZyme® bring important advantages to users in biopharmaceutical research and industry, overcoming limitations of the LAL test (Limulus amebocyte lysate) which still relies on lysate from the blood of the horseshoe (Limulus) crab. In 2014, Hyglos first introduced the Endo-RS® Endotoxin Recovery Method, overcoming Masking of Endotoxin which causes Low Endotoxin Recovery (LER) addressed by the FDA.

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EndoLISA Video User Guide: